Coagulation profiles and viscoelastic testing in multisystem inflammatory syndrome in children.
Ashish A AnkolaVictoria R BradfordJane W NewburgerSirisha EmaniAudrey DionneKevin FriedmanMary Beth SonLauren A HendersonPui Y LeeAmy HellingerBeth HawkinsCourtney VentrescoPaul EstesoChristina J VanderPluymPublished in: Pediatric blood & cancer (2021)
Patients with MIS-C had evidence of hypercoagulability on TEG. Increased ESR and platelets were associated with higher clot strength. Patients were prophylactically treated with ASA or anticoagulation with no symptomatic thrombosis or major bleeding. Further multicenter study is required to characterize the rate of thrombosis and optimal thromboprophylaxis algorithm in this patient population.
Keyphrases
- end stage renal disease
- newly diagnosed
- pulmonary embolism
- venous thromboembolism
- atrial fibrillation
- chronic kidney disease
- case report
- ejection fraction
- young adults
- machine learning
- prognostic factors
- oxidative stress
- deep learning
- direct oral anticoagulants
- patient reported outcomes
- high resolution
- atomic force microscopy
- neural network
- red blood cell