Associations of Amyloid Burden, White Matter Hyperintensities, and Hippocampal Volume With Cognitive Trajectories in the 90+ Study.
Jingxuan WangSarah F AckleyDavis C WoodworthSeyed Ahmad SajjadiCharles S DecarliEvan F FletcherMedellena Maria GlymourLuohua JiangClaudia H KawasMaría M CorradaPublished in: Neurology (2024)
Amyloid burden and hippocampal atrophy are associated with both cognitive level and cognitive decline in the oldest old. Our findings shed light on how different pathologies contributed to driving cognitive function in the oldest old.