The incidence, risk factors, and outcomes of symptomatic avascular necrosis of bone among Chinese pediatric patients with acute lymphoblastic leukemia.
Calvin Pui Lun HooAlex Wing Kwan LeungJoyce Pui Kwan ChanYin Ting CheungFrankie Wai Tsoi ChengTerry Tin Wai ChowGrace Kee See LamSau Yin HaAlan Kwok Shing ChiangRever Chak Ho LiChi-Kong LiPublished in: Cancer medicine (2023)
The incidence of symptomatic AVN in Chinese ALL patients was comparable to other studies in Western population. Adolescent age more than 10 years old was recognized to be the most important factor for development of AVN. Significant proportion of patients had radiological progression over time with a small percentage of subjects had daily activities affected.