Sirolimus-exuding core-shell nanofibers as an implantable carrier for breast cancer therapy: preparation, characterization, in vitro cell studies, and in vivo anti-tumor activity.
Rozhin TalimiZahra ShahsavariSimin DadashzadehTimo L M Ten HagenAzadeh HaeriPublished in: Drug development and industrial pharmacy (2023)
Altogether, we show here that incorporation of SIR into core-shell NFs could act as an effective drug release depot and induce a sustained antitumor response.