Exome sequencing of Japanese schizophrenia multiplex families supports the involvement of calcium ion channels.

Miho ToyamaYuto TakasakiAleksic BrankoHiroki Kimura Hidekazu KatoYoshihiro NawaItaru KushimaKanako IshizukaTeppei ShimamuraTomoo OgiNorio Ozaki

Published in: PloS one (2022)

This study provides supporting evidence that calcium ion channel activity is involved in SCZ. WES of multiplex families is a potential means of identifying disease-associated rare variants for SCZ.

Keyphrases

copy number
high throughput
bipolar disorder
real time pcr
gene expression
risk assessment
dna methylation