Prognosis of pediatric ulcerative colitis after infliximab failure: A multicenter registry-based cohort study.

Ryusuke Nambu Takahiro KudoNao TachibanaHirotaka Shimizu Tatsuki MizuochiSawako KatoMikihiro InoueHideki KumagaiTakashi IshigeReiko KunisakiAtsuko NoguchiToshifumi YodoshiShin-Ichiro HagiwaraShigeo NishimataFumihiko KakutaTakeshi SaitoItaru IwamaYuri HiranoToshiaki ShimizuKatsuhiro Arainull null

Published in: Journal of gastroenterology and hepatology (2023)

In pediatric UC patients, approximately 50% underwent colectomy during a 2-year interval following IFX failure. Prognosis after IFX failure appeared to improve with availability of new biologic agents and small-molecule drugs in mid-2018.

Keyphrases

small molecule
ulcerative colitis
end stage renal disease
newly diagnosed
ejection fraction
rheumatoid arthritis
chronic kidney disease
peritoneal dialysis
prognostic factors
clinical trial
protein protein
patient reported outcomes
drug induced
childhood cancer