Risk Factors for Incident Diabetic Polyneuropathy in a Cohort With Screen-Detected Type 2 Diabetes Followed for 13 Years: ADDITION-Denmark.

Signe Toft AndersenDaniel R WitteElse-Marie DalsgaardHenning AndersenPeter NawrothThomas FlemingTroels M JensenNanna B FinnerupTroels S JensenTorsten LauritzenEva L FeldmanBrian Christopher CallaghanMorten Charles

Published in: Diabetes care (2018)

This study provides further epidemiological evidence for obesity as a risk factor for DPN. Moreover, low HDL cholesterol levels and higher levels of methylglyoxal, a marker of dicarbonyl stress, are identified as risk factors for the development of DPN.

Keyphrases

type diabetes
insulin resistance
cardiovascular disease
metabolic syndrome
high throughput
weight loss
skeletal muscle
wound healing
low density lipoprotein
high fat diet induced
physical activity