An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study.
Peter SzmukDean AndropoulosFrancis McGowanAnsgar BrambrinkChristopher LeeKatherine J LeeMary Ellen McCannYang LiuRita SaynhalathChoon Looi BongBrian Joseph AndersonCharles BerdeJurgen C de GraaffNicola DismaDean KurthAndreas LoepkeBeverley OrserDaniel I SesslerJustin J SkownoBritta Sylvia von Ungern-SternbergLaszlo VutskitsAndrew DavidsonPublished in: Paediatric anaesthesia (2019)
A dexmedetomidine/remifentanil neuraxial anesthetic regimen was effective in 87.5% of infants. These findings can be used as a foundation for designing larger trials that assess alternative anesthetic regimens for anesthetic neurotoxicity in infants.