Effect of Deep Brain Stimulation on Parkinson Disease Dementia: A Systematic Review and Meta-analysis.
Ali RazmkonSaeed AbdollahifardHirad RezaeiAmir Reza BahadoriParham EskandarzadehAmirAli Rastegar KazerooniPublished in: Basic and clinical neuroscience (2024)
Our results suggest that the STN-DBS group showed a larger cognitive decline than the patients receiving the best medical treatment (BMT). However, comparing STN-DBS with globus pallidus interna stimulation and pallidotomy could not demonstrate a significant statistical effect on the global dementia of patients. More long-term studies with larger sample sizes are needed to validate current findings.
Keyphrases
- deep brain stimulation
- parkinson disease
- mild cognitive impairment
- cognitive decline
- obsessive compulsive disorder
- end stage renal disease
- cognitive impairment
- ejection fraction
- newly diagnosed
- healthcare
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- patient reported outcomes
- combination therapy
- replacement therapy