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Regional hippocampal atrophy reflects memory impairment in patients with early relapsing remitting multiple sclerosis.

Rosa CorteseMarco BattagliniMaria Laura StromilloLudovico LuchettiMatteo LeonciniGiordano GentileDaniele GaspariniDomenico PlantoneManuela AltieriAlessandro D'AmbrosioAntonio GalloCostanza GiannìClaudia PiervincenziPatrizia PantanoElisabetta PaganiPaola ValsasinaPaolo PreziosaNicolo' TedoneMaria Assunta RoccaMassimo FilippiNicola De Stefanonull null
Published in: Journal of neurology (2024)
Hippocampal atrophy spreads from CA to tail from early disease stages. Subfield hippocampal atrophy is associated with memory impairment in MMI-MS, while this correlation is lost in SMI-MS. This plays in favor of a limited capacity for an adaptive functional reorganization of the hippocampi in MS patients.
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