Similar progression of carotid intima-media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients.
Sofia AjeganovaThomas GustafssonLinnea LindbergIngiäld HafströmJohan FrostegårdPublished in: Lupus science & medicine (2020)
We observed a statistically comparable progression of cIMT in patients with mild SLE and controls over 7 years, which implies that progression of subclinical atherosclerosis in some patients with SLE could follow that of the general population. Traditional cardiovascular (CV) risk factors, history of lupus nephritis and higher use of corticosteroids promote cIMT progression in SLE. Detection of carotid plaque may add to CV risk stratification.
Keyphrases
- systemic lupus erythematosus
- disease activity
- risk factors
- blood pressure
- end stage renal disease
- public health
- newly diagnosed
- ejection fraction
- rheumatoid arthritis
- coronary artery disease
- peritoneal dialysis
- optical coherence tomography
- prognostic factors
- cardiovascular risk factors
- quantum dots
- patient reported outcomes