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BIO 300, a nanosuspension of genistein, mitigates pneumonitis/fibrosis following high-dose radiation exposure in the C57L/J murine model.

Isabel L JacksonAndrew ZoddaGanga GurungRadmila PavlovicMichael D KaytorMichael A KuskowskiZeljko Vujaskovic
Published in: British journal of pharmacology (2017)
BIO 300 is a promising MCM candidate to mitigate pneumonitis/fibrosis when administered daily for 4-6 weeks starting 24 h post-exposure.
Keyphrases
  • high dose
  • interstitial lung disease
  • low dose
  • stem cell transplantation
  • physical activity
  • liver fibrosis
  • gestational age
  • idiopathic pulmonary fibrosis
  • preterm birth