Prognostic impact of platinum sensitivity in ovarian carcinoma patients with brain metastasis.
Alexandre Andre Balieiro Anastacio da CostaElizabeth Santana Dos SantosDeborah Porto CotrimNatasha Carvalho PandolfiMarcelle Goldner CescaHenrique MantoanSolange Moraes SanchesAdriana Regina Gonçalves RibeiroLouise de BrotGraziele BonvolimPaulo Issamu SanematsuRonaldo Pereira de SouzaJoyce Maria Lisboa MayaFabrício de Souza CastroJoão Paulo da Nogueira Silveira LimaMichael Jenwel ChenAndrea Paiva Gadelha GuimarãesGlauco BaiocchiPublished in: BMC cancer (2019)
The factors related to the biological behavior of the ovarian cancer such as platinum sensitivity at the time of BM diagnosis, fewer number of previous treatment lines and interval from initial diagnosis were associated with survival in ovarian cancer patients with BM, while factors that are usually related to survival in BM in other cancers were not associated with survival in this cohort of ovarian cancer patients. The small number of patients did not allow us to exclude the prognostic role of these former factors that were not associated with survival in the present cohort.