Radiotherapy-Induced Atrial Myxoma: A Case Report and Literature Review.
Walid ShalataIsmaell MassalhaShlomo Yaron IshayElena ChernomordikovaAshraf Abu JamaKeren RouvinovYulia DudnikAlexander YakobsonPublished in: Life (Basel, Switzerland) (2023)
In this particular case study, we present a 66-year-old male who was diagnosed with an atrial myxoma eight years after receiving treatment for non-small cell lung cancer. The patient underwent chemo-radiotherapy (mediastinal area) in 2012 to address stage III-A adenocarcinoma of the lung. During follow-up imaging in 2020, a left atrial mass displaying characteristic features of a cardiac myxoma was detected. Upon reviewing a computed tomographic (CT) scan from 2017 within the previously irradiated mediastinal region, the cardiac mass was retrospectively identified. The surgical excision of the cardiac mass was performed, and a subsequent pathological examination confirmed the diagnosis of myxoma. To the best of our knowledge, this is the first reported case of a left atrial myxoma in a patient previously treated for adenocarcinoma of the lung and the first instance of an atrial myxoma occurring in a site that had undergone prior radiation therapy.
Keyphrases
- left atrial
- left ventricular
- atrial fibrillation
- locally advanced
- radiation therapy
- mitral valve
- catheter ablation
- squamous cell carcinoma
- early stage
- computed tomography
- lymph node
- rectal cancer
- case report
- radiation induced
- combination therapy
- ultrasound guided
- high resolution
- magnetic resonance imaging
- photodynamic therapy
- drug delivery
- high glucose
- smoking cessation
- diabetic rats
- positron emission tomography