Biologically Targeted Radiation Therapy: Incorporating Patient-Specific Hypoxia Data Derived from Quantitative Magnetic Resonance Imaging.
Emily J HerAnnette HaworthYu SunScott WilliamsHayley M ReynoldsAngel KennedyMartin A EbertPublished in: Cancers (2021)
Results of this study suggest the use of mpMRI for voxel-level targeting of hypoxia, along with biological optimisation, can provide a mechanism for guiding focal DE that is considerably more efficient than application of a general, dose-based optimisation, focal boost.