Effects of Cochlear Implantation and Steroids on the Aging Guinea Pig Cochlea.
Jeffrey M HyzerJordan D HillWenxuan HeGeorge W S BurwoodAdrienne K FettigLina A J ReissPublished in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2024)
Young animals and older animals that received steroids had better hearing after CI than older animals not given steroids, but hearing preservation was not correlated with the level of fibrosis assessed using OCT. This work is the first to investigate differences in hearing preservation by age in an animal model, and supports the protective effects of steroids on hearing preservation in older individuals.