Common variants of EDA are associated with non-syndromic hypodontia.

Azza H Al-AniJoseph S AntounWilliam M ThomsonRuth ToplessTony R MerrimanMauro Farella

Published in: Orthodontics & craniofacial research (2020)

Common variants of the EDA genes are associated with specific phenotypes of non-syndromic hypodontia, thus confirming their role in the regulatory pathways of normal tooth development. However, larger samples are needed to investigate the association further.

Keyphrases

intellectual disability
copy number
genome wide
transcription factor
autism spectrum disorder
dna methylation
bioinformatics analysis
gene expression