Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway.

Ali A ShatiMohammed A AlkahtaniMohamed Y AlfaifiSerag Eldin I ElbehairiFahmy Gad ElsaidRajagopalan PrasannaMushtaq Ahmad Mir

Published in: BioMed research international (2020)

These results suggest that the S. costus extract is the potential source of the secondary metabolites that could be used as anticancer agent to treat diverse cancers of breast, colon, and liver.

Keyphrases

ms ms
oxidative stress
cell death
endoplasmic reticulum stress
cell cycle arrest
induced apoptosis
risk assessment
signaling pathway