Spermatozoa from males with reduced fecundity exhibit differential DNA methylation patterns.

Mohammed M LaqqanS TierlingY AlkhaledC Lo PortoE F SolomayerM Hammadeh

Published in: Andrology (2017)

In conclusion, an alteration in the methylation levels of sperm DNA from males with reduced fecundity was observed. In addition, an association between changes in the methylation level for these CpGs and different semen parameters has been found.

Keyphrases

dna methylation
genome wide
gene expression
circulating tumor
single molecule
copy number
nucleic acid