Feline giant-cell pleomorphic sarcoma: cytologic, histologic and immunohistochemical characterization.
Bianca Santana de CeccoFernando Froner ArgentaRonaldo M BianchiCíntia De LorenzoJúlia G WronskiMarcele B BandinelliFernanda Vieira Amorim da CostaDavid DriemeierSaulo P PavariniLuciana SonnePublished in: Journal of feline medicine and surgery (2020)
PS is a neoplasm of mesenchymal origin, also known as malignant fibrous histiocytoma. The predominant subtype in this study that affected the cats was the giant-cell type, characterized by the presence of multinucleated giant cells among spindle-shaped cells. These findings are similar to those described in human patients; thus, a comparison between the neoplasms seen in these species might be useful, and the knowledge of biologic behavior and overall treatment approach for humans could be extrapolated to cats.
Keyphrases
- endoplasmic reticulum stress
- induced apoptosis
- giant cell
- end stage renal disease
- healthcare
- rheumatoid arthritis
- newly diagnosed
- stem cells
- ejection fraction
- cell cycle arrest
- bone marrow
- prognostic factors
- peritoneal dialysis
- cell death
- cell proliferation
- signaling pathway
- rare case
- patient reported outcomes
- replacement therapy
- patient reported