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Danlou Tablet May Alleviate Vascular Injury Caused by Chronic Intermittent Hypoxia through Regulating FIH-1, HIF-1, and Angptl4.

Yi RongQian WuJingjing TangZhiguo LiuQianyu LvXuejiao YeYu DongYuebo ZhangGuangxi LiShihan Wang
Published in: Evidence-based complementary and alternative medicine : eCAM (2022)
DLT improved vascular damage by improving the increase in blood lipids induced by CIH, potentially by upregulating FIH-1 and downregulating HIF-1 and Angptl4 in adipose tissue. Therefore, DLT may be a promising agent for the prevention and treatment of CIH-induced vascular injury.
Keyphrases
  • adipose tissue
  • endothelial cells
  • oxidative stress
  • type diabetes
  • insulin resistance
  • diabetic rats
  • drug induced
  • skeletal muscle
  • combination therapy