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Comparative Anticoagulant and Thrombin Generation Inhibitory Profile of Heparin, Sulodexide and Its Components.

Fakiha SiddiquiDebra Moorman HoppensteadtEmily BontekoeAmbar FarooquiWalter JeskeJawed Fareed
Published in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2020)
In comparison to sulodexide, both UFH and FMH exhibit comparable anticoagulant activity despite differences in their molecular weight. These results suggest that sulodexide can be developed as a parenteral anticoagulant for indications in which UFH is used.
Keyphrases
  • venous thromboembolism
  • atrial fibrillation
  • growth factor