Search Behavior Regarding Cancer Susceptibility Genes Using a Clinical Decision Support Tool for Gene-Specific Penetrance: Content Analysis.
Kanhua YinJingan ZhouPreeti SinghJin WangDanielle BraunKevin S HughesPublished in: JMIR cancer (2021)
The patients entered in the Ask2Me.org tool are a representative cohort of patients with pathogenic variants in cancer susceptibility genes in the United States. While a majority of the queries were on breast cancer susceptibility genes, users also queried susceptibility genes with lower prevalence, which may represent a transformation from single gene testing to multigene panel testing. Owing to these changing tides, more efforts are needed to improve evidence-based clinical decision support tools to better aid clinicians and their practice.
Keyphrases
- clinical decision support
- genome wide
- genome wide identification
- copy number
- electronic health record
- papillary thyroid
- genome wide analysis
- bioinformatics analysis
- end stage renal disease
- transcription factor
- squamous cell
- healthcare
- newly diagnosed
- primary care
- palliative care
- ejection fraction
- peritoneal dialysis
- risk factors
- childhood cancer
- lymph node metastasis
- young adults