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Polygenic risks for joint developmental trajectories of internalizing and externalizing problems: findings from the ALSPAC cohort.

Lydia Gabriela SpeyerSamuel NeavesHildigunnur Anna HallGibran HemaniMichael Vincent LombardoAja Louise MurrayBonnie AuyeungMichelle Luciano
Published in: Journal of child psychology and psychiatry, and allied disciplines (2021)
While affected classes could be relatively well separated from the unaffected class, phenotypic and polygenic predictors were limited in their ability to distinguish between different affected classes. Results thus add to existing evidence that internalizing and externalizing problems have mostly shared risk factors.
Keyphrases
  • mental health
  • risk factors
  • human health
  • risk assessment