Delta-Omicron recombinant escapes therapeutic antibody neutralization.

Ralf DuerrHao ZhouTakuya TadaDacia DimartinoChristian MarierPaul ZappileGuiqing WangJonathan PlitnickSara B GriesemerRoxanne GirardinJessica MachowskiSean BialosukniaErica Lasek-NesselquistSamuel L HongGuy BaeleMeike DittmannMila B OrtigozaPrithiv J PrasadKathleen McDonoughNathaniel R LandauKirsten St GeorgeAdriana Heguy

Published in: bioRxiv : the preprint server for biology (2022)

Recombination between circulating SARS-CoV-2 variants can functionally contribute to immune escape. It is critical to validate phenotypes of mosaic viruses and monitor immunosuppressed COVID-19 patients treated with monoclonal antibodies for the selection of recombinant and immune escape variants. (Funded by NYU, the National Institutes of Health, and others).

Keyphrases

sars cov
copy number
respiratory syndrome coronavirus
coronavirus disease
healthcare
public health
cell free
dna damage
mental health
quality improvement
dna repair
gene expression
health information
oxidative stress
risk assessment
genetic diversity