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Protective Effects of Liposomal Curcumin on Oxidative Stress/Antioxidant Imbalance, Metalloproteinases 2 and -9, Histological Changes and Renal Function in Experimental Nephrotoxicity Induced by Gentamicin.

Adriana Elena BulboacăPaul-Mihai BoarescuSorana D BolboacăCristina Ariadna NiculaDana Gabriela FeștilăDana Gabriela FeștilăRuxandra Mioara RâjnoveanuRuxandra Mioara RâjnoveanuArmand-Gabriel RajnoveanuPaul-Mihai BoarescuVasile RusCorneliu Angelo BulboacăIoana Cristina StanescuIoana Stănescu
Published in: Antioxidants (Basel, Switzerland) (2021)
Our results demonstrated improving renal function and kidney cytoarchitecture, oxidative stress/antioxidant/balance, and MMPs plasma concentrations with better dose-related efficacity of LCC than CC.
Keyphrases
  • oxidative stress
  • diabetic rats
  • ischemia reperfusion injury
  • dna damage
  • induced apoptosis
  • anti inflammatory
  • drug induced
  • signaling pathway