Association of combination statin and antihypertensive therapy with reduced Alzheimer's disease and related dementia risk.
Douglas BartholdGeoffrey JoyceRoberta Diaz BrintonWhitney WhartonPatrick Gavin KehoeJulie ZissimopoulosPublished in: PloS one (2020)
Among older Americans, use of pravastatin and rosuvastatin to treat hyperlipidemia is less common than use of simvastatin and atorvastatin, however, in combination with RAS-acting AHTs, particularly ARBs, they may be more effective at reducing risk of ADRD. The number of Americans with ADRD may be reduced with drug treatments for vascular health that also confer effects on ADRD.
Keyphrases
- mild cognitive impairment
- healthcare
- public health
- blood pressure
- cognitive decline
- cardiovascular disease
- mental health
- coronary artery disease
- high fat diet
- cognitive impairment
- health information
- stem cells
- type diabetes
- adipose tissue
- risk assessment
- skeletal muscle
- adverse drug
- insulin resistance
- human health
- electronic health record
- cell therapy