Comparative effects of the antioxidant glutathione with metformin and Diane-35 on hormonal, metabolic, and inflammatory indicators in a DHEA-induced PCOS rat model.
Aslı CoşarPınar ÖzcanFatma Basak TanogluOlgu Enis TokGülçin ÖzkaraHikmet Tunç TimurÇağlar ÇetinDuygu NeccarPublished in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2024)
Glutathione plays anti-inflammatory and antioxidant roles, similar to metformin, by lowering serum IL-6, insulin, testosterone, CRP, and MDA levels; decreasing atretic/cystic follicle count; and improving antral follicle count and folliculogenesis in PCOS patients.
Keyphrases
- anti inflammatory
- polycystic ovary syndrome
- oxidative stress
- end stage renal disease
- ejection fraction
- type diabetes
- chronic kidney disease
- prognostic factors
- diabetic rats
- peritoneal dialysis
- cell death
- glycemic control
- breast cancer cells
- drug induced
- patient reported outcomes
- endothelial cells
- cell cycle arrest
- patient reported