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Thioredoxin reductase 1 regulates hepatic inflammation and macrophage activation during acute cholestatic liver injury.

Colin T ShearnAimee L AndersonColin G MillerReed C NoydMichael W DevereauxNata BalasubramaniyanDavid J OrlickyEdward E SchmidtRonald J Sokol
Published in: Hepatology communications (2023)
These data implicate TrxR1-signaling as an important regulator of inflammation and bile acid homeostasis in cholestatic liver injury.
Keyphrases
  • liver injury
  • drug induced
  • oxidative stress
  • electronic health record
  • adipose tissue
  • liver failure
  • transcription factor
  • hepatitis b virus
  • data analysis
  • acute respiratory distress syndrome