Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy.
Bruce D LeckeyMeenal K KheterpalM Angelica SelimRami Nayef Al-RohilPublished in: Journal of cutaneous pathology (2021)
T-cell prolymphocytic leukemia (T-PLL) is a rare, aggressive neoplasm derived from post-thymic T-cells. Patients are typically middle aged with a slight male predominance who present with a high white blood cell count, hepatosplenomegaly, lymphadenopathy, and other symptoms typically associated with leukemia. Although cutaneous involvement has been reported in up to 30% of cases of T-PLL, to our knowledge, none have presented with a presentation resembling livedoid vasculopathy. In the correct clinical context, an underlying hematolymphoid neoplasm should be included in the differential diagnosis of a patient presenting with livedoid vasculopathy.