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Gestational hypertensive disorders and blood pressure and childhood cardiac outcomes: A prospective cohort study.

Meddy N Bongers-KarmaouiClarissa J WiertsemaAnnemarie G M G J MuldersWim A HelbingAlexander HirschArno A W RoestVincent W V JaddoeRomy Gaillard
Published in: BJOG : an international journal of obstetrics and gynaecology (2023)
No consistent associations of gestational hypertensive disorder status with childhood cardiac outcomes were present. Higher maternal DBP throughout pregnancy was associated with lower childhood LVEDVs and RVEDVs. Stronger maternal-offspring rather than paternal-offspring associations were present, which may suggest that suboptimal maternal gestational haemodynamic adaptations affects offspring cardiac structure through direct intrauterine effects. Further studies are needed to replicate these findings and examine the underlying mechanisms.
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