The impact of comparative genomic hybridization/single-nucleotide polymorphism microarray in risk stratification of pediatric acute lymphoblastic leukemia.
Antoine GourmelHéloïse PerraultMarie-Laure ColaiacovoLouise LaraméeMarieke RozendaalHenrique BittencourtCaroline LaverdièreJosette ChampagneSonia CellotLewis B SilvermanEmmanuelle LemyreCatalina MafteiGéraldine MathonnetFrédérique TihyMarie-Claude Pelland-MarcotteFrance LéveilléThai Hoa TranPublished in: Pediatric blood & cancer (2024)
CGH/SNP provided faster, reliable, and highly concordant results than those obtained by conventional cytogenetics. CGH/SNP identified recurrent gene deletions in pediatric ALL, of which ETV6 deletion conferred a favorable prognosis.