Therapeutic Potential of Silymarin in Mitigating Paclitaxel-Induced Hepatotoxicity and Nephrotoxicity: Insights into Oxidative Stress, Inflammation, and Apoptosis in Rats.

Seda Yakut Tuğçe Atçalı Cüneyt Çaglayan Aykut Ulucan Fatih Mehmet Kandemir Adem Kara Turgut Anuk

Published in: Balkan medical journal (2024)

Our findings indicate the potential of SIL to alleviate PAX-induced liver and kidney damage in rats by reducing oxidative stress, inflammation, and apoptotic processes.

Keyphrases

oxidative stress
diabetic rats
drug induced
ischemia reperfusion injury
dna damage
induced apoptosis
high glucose
cell death
heat shock
risk assessment
endoplasmic reticulum stress
human health
signaling pathway
heat stress
pi k akt