Colorectal polyps: Targets for fluorescence-guided endoscopy to detect high-grade dysplasia and T1 colorectal cancer.
Nik DekkersElham ZonoobiHao DangMats I WarmerdamStijn CrobachAlexandra M J LangersJolein van der KraanDenise E HillingKoen C M J PeetersFabian A HolmanAlexander L VahrmeijerCornelis F M SierJames C H HardwickJurjen J BoonstraPublished in: United European gastroenterology journal (2023)
Of the tested targets, CEA appears the most suitable to specifically detect HGD and T1 cancer foci in colorectal polyps. An in vivo study using tumor-targeted fluorescence-guided endoscopy should confirm these findings.