Introduction of hsa-miR-512-3p as a new regulator of HER2 signaling pathway in breast cancer.

Zahra MohamadzadeFrouzande MahjoubiBahram Mohammad Soltani

Published in: Breast cancer research and treatment (2020)

Overall, results indicated that miR-512-3p acts as a cell-type-specific tumor suppressor, through targeting HER2, HER3, PIK3R2, and AKT1 transcripts. These results suggest miR-512-3p as a potential candidate marker for breast cancer diagnosis.

Keyphrases

signaling pathway
epithelial mesenchymal transition
transcription factor
cancer therapy
risk assessment
oxidative stress
endoplasmic reticulum stress