Serum Cell-free DNA-based Detection of Mycobacterium Avium Complex Infection.

Lin LiEmily HenkleBrady M YoungquistSeungyeon SeoKamal A HamedDavid MelnickChristopher J LyonLi JiangAdrian M ZelaznyTony Y HuKevin L WinthropBo Ning

Published in: American journal of respiratory and critical care medicine (2024)

This study provides preliminary evidence for the utility of a serum-based CRISPR-MAC assay to rapidly detect MAC infection and monitor their response to treatment.

Keyphrases

mycobacterium tuberculosis
crispr cas
high throughput
gene expression
loop mediated isothermal amplification
combination therapy