Immunothrombosis: Molecular Aspects and New Therapeutic Perspectives.
María Marcos-JubilarRamón LecumberriJose Antonio ParamoPublished in: Journal of clinical medicine (2023)
Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the current data regarding the mechanisms involved in immunothrombosis in order to understand the new therapeutic strategies focused in reducing thrombotic risk by controlling the inflammation.
Keyphrases
- venous thromboembolism
- inflammatory response
- coronavirus disease
- sars cov
- oxidative stress
- direct oral anticoagulants
- acute kidney injury
- lipopolysaccharide induced
- intensive care unit
- electronic health record
- lps induced
- septic shock
- big data
- toll like receptor
- machine learning
- single molecule
- respiratory syndrome coronavirus
- deep learning