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Successful pregnancy after 10 consecutive failures in a liver transplant patient with advanced kidney failure.

Leonard CauchyEve MoustyGeorge-Philippe PageauxOlivier Moranne
Published in: Journal of nephrology (2024)
We report a successful, albeit complicated pregnancy with a live-born healthy baby at 28 weeks' gestation, after 10 pregnancy failures, in a 39-year-old patient with a history of liver transplantation and chronic kidney disease with hypertension and proteinuria. Multidisciplinary management (obstetrician, nephrologist and hepatology transplant specialist) allowed close monitoring, adaptation of immunosuppressive treatments and strict control of fetal growth. The onset of preeclampsia at 28 weeks' gestation led to a cesarean section, resulting in the birth of a healthy 830 g boy, with subsequent normal development. Following pregnancy, the patient experienced liver transplant rejection, which resolved after adapting immunosuppressive drugs. No deterioration in kidney function was observed in the year following delivery.
Keyphrases
  • gestational age
  • preterm birth
  • pregnancy outcomes
  • case report
  • chronic kidney disease
  • low birth weight
  • blood pressure
  • pregnant women
  • early onset
  • quality improvement