Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon.
Julia MatasBrendan F KohrnJeanne FredricksonKelly T CarterMing YuTing WangXianyong GuiThierry SoussiVictor MorenoWilliam M GradyMiguel A PeinadoRosa Ana RisquesPublished in: Cancer research (2022)
This work suggests prevalent somatic evolution in the normal colon of patients with colorectal cancer, highlighting the potential of using ultrasensitive gene sequencing to predict disease risk.