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Podocyte Density and Albuminuria in Aging Diabetic Ins2± Mice with or Without Adenosine A1 Receptor Signaling.

Robert Faulhaber-WalterLanping JiangDiane MizelPatricia M ZerfasJeffrey B KoppJurgen B SchnermannLimeng ChenMario Schiffer
Published in: International journal of nephrology and renovascular disease (2020)
The amount of albuminuria as marker of diabetic nephropathy does not correlate with the podocytes density; however, a relative podocyte deficiency became evident with an increase in glomerular area in the diabetic animals, suggesting a relative podocytopenia.
Keyphrases
  • diabetic nephropathy
  • type diabetes
  • wound healing
  • high fat diet induced
  • insulin resistance
  • protein kinase
  • skeletal muscle