Cerebellar Ataxia With Anti-DNER Antibodies: Outcomes and Immunologic Features.
Elise PeterLe Duy DoSalem HannounSergio Muñiz-CastrilloAlberto VogrigValentin WucherAnne-Laurie PintoNaura ChounlamountriWalaa ZakariaVéronique RogemondGeraldine PicardJulien-Jacques HedouAditya AmbatiAgusti AlentornAlexandra Traverse-GlehenMario MantoDimitri PsimarasEmmanuel MignotFrançois CottonVirginie DesestretJérôme HonnoratBastien JoubertPublished in: Neurology(R) neuroimmunology & neuroinflammation (2022)
DNER ataxia is a treatable condition in which nearly a third of patients have a favorable outcome. DNER antibodies bind to the surface of Purkinje cells and are therefore potentially pathogenic, supporting the use of B-cell-targeting treatments.