Intramuscular Administration of Tranexamic Acid in a Large Swine Model of Hemorrhage with Hyperfibrinolysis.

Christopher J HaberkornCarter C SeveranceNathan C WetmoreWalker G WestPatrick C NgFrancesca CendaliChristopher PitottiL T C Steven G SchauerJoseph K MaddryCol Vikhyat S Bebarta Tara B Hendry-Hofer

Published in: The journal of trauma and acute care surgery (2023)

In the large swine model of hemorrhage with hyperfibrinolysis, IM TXA is bioequivalent and equally efficacious in preventing hyperfibrinolysis as IV TXA administration.

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