Adipose Tissue Sex Steroids in Postmenopausal Women with and without Menopausal Hormone Therapy.

Natalia HetemäkiAlexandra RobciucVeera VihmaMikko HaanpääEsa HämäläinenMatti J TikkanenTomi S MikkolaHanna Savolainen-Peltonen

Published in: The Journal of clinical endocrinology and metabolism (2024)

Higher local estrogen to androgen ratios and high AT to serum ratios of estrogen concentrations in HT users suggest that HT may significantly influence intracrine sex steroid metabolism in AT, and these local changes could be involved in the preventive effect of HT on menopause-associated abdominal adiposity.

Keyphrases

postmenopausal women
bone mineral density
adipose tissue
insulin resistance
estrogen receptor
high fat diet
type diabetes
stem cells
weight gain
physical activity
mesenchymal stem cells
replacement therapy