Evaluation of memantine's efficacy and safety in the treatment of children with autism spectrum disorder: A systematic review and meta-analysis.
Walaa ElnaiemAmira Yasmine BenmeloukaAli Mohamed Naguib ElgendyMahmoud Shaban AbdelgalilMuhamad Zakaria Brimo AlsamanAly MogheethMahmoud M AliShimaa Mohammad YousofPublished in: Human psychopharmacology (2022)
Memantine showed safety in reducing acute symptoms of anxiety and other symptoms encountered in pediatric patients with autism spectrum disorders. However, memantine does not improve the core symptoms of autism. Nevertheless, further long-term trials are needed to explore its potential efficacy.