Structured 3' UTRs destabilize mRNAs in plants.

Tianru ZhangChanghao LiJiaying ZhuYanjun LiZhiye WangChun-Yip TongYu XiYi HanHisashi KoiwaXu PengXiuren Zhang

Published in: Genome biology (2024)

We conclude that highly structured 3' UTRs typically cause reduced accumulation of the harbored transcripts in Arabidopsis. This pattern extends to rice and even mammals. Furthermore, our study provides a new strategy of engineering the 3' UTRs' RSS to modify plant traits in agricultural production and mRNA stability in biotechnology.

Keyphrases

transcription factor
risk assessment
heavy metals
genome wide
gene expression
binding protein
human health
dna methylation