Primary Ovarian Leiomyosarcoma Is a Very Rare Entity: A Narrative Review of the Literature.
Vincenzo Dario MandatoFederica TorricelliValentina MastrofilippoAndrea PalicelliLuigi CostagliolaLorenzo AguzzoliPublished in: Cancers (2023)
Primary ovarian leiomyosarcomas are more common in women in their 50s (mean age 53 years). Most of them are at an early stage at presentation. Advanced stage and mitotic count showed a detrimental effect on survival. Surgical excision associated with lymphadenectomy and chemotherapy are associated with increased survival. An international registry could help collect clear and reliable data to standardize the diagnosis and treatment.
Keyphrases
- early stage
- sentinel lymph node
- polycystic ovary syndrome
- free survival
- lymph node
- type diabetes
- cell cycle
- big data
- case report
- lymph node metastasis
- locally advanced
- peripheral blood
- pregnancy outcomes
- pregnant women
- metabolic syndrome
- cell proliferation
- adipose tissue
- insulin resistance
- minimally invasive
- chemotherapy induced
- data analysis