Benzyl sulforaphane is superior to sulforaphane in inhibiting the Akt/MAPK and activating the Nrf2/ARE signalling pathways in HepG2 cells.

Jie RenLing YuanYue WangGuangtong ChenKun Hu

Published in: The Journal of pharmacy and pharmacology (2018)

Benzyl sulforaphane was superior to SFN in inhibiting Akt/MAPK and activating Nrf2/ARE signalling pathways in HepG2 cells, which indicated that BSFN could be a safe therapeutic strategy for the prevention and treatment of liver cancer.

Keyphrases

signaling pathway
pi k akt
oxidative stress
cell proliferation
replacement therapy
smoking cessation