Simulating progressive motor neuron degeneration and collateral reinnervation in motor neuron diseases using a dynamic muscle model based on human single motor unit recordings.

Boudewijn T H M SleutjesDiederik J L Stikvoort GarcíaPieter A van DoornH Stephan GoedeeLeonard H van den Berg

Published in: Journal of neural engineering (2023)

percentile = -4.0-+2.4 mV). Significance: The dynamic muscle model could be used as a platform to train personnel in applying surface-EMG methods prior to their use in clinical care and trials. Moreover, The model may pave the way to compare biomarkers more efficiently, without directly posing unnecessary burden on patients.

Keyphrases

skeletal muscle
end stage renal disease
endothelial cells
newly diagnosed
ejection fraction
multiple sclerosis
palliative care
prognostic factors
risk factors
pain management
chronic pain
health insurance
high density