Association Between Postsurgical Functional Connectivity and Seizure Outcome in Patients With Temporal Lobe Epilepsy.
Behnaz AkbarianLucas E SainburgAndrew JansonGraham JohnsonDerek J DossBaxter P RogersDario J EnglotVictoria L MorganPublished in: Neurology (2024)
The findings suggest that network evolution in the first 5 years after selective amygdalohippocampectomy surgery is related to seizure outcomes in TLE. This highlights the need to identify presurgical and surgical conditions that lead to disparate postsurgical trajectories between seizure-free and nonseizure-free patients to identify potential contributors to long-term seizure outcomes. However, the lack of including other surgical approaches may affect the generalizability of the results.
Keyphrases
- temporal lobe epilepsy
- functional connectivity
- resting state
- end stage renal disease
- ejection fraction
- minimally invasive
- newly diagnosed
- chronic kidney disease
- depressive symptoms
- prognostic factors
- peritoneal dialysis
- type diabetes
- metabolic syndrome
- patient reported outcomes
- skeletal muscle
- climate change
- glycemic control
- atrial fibrillation