Building-block exchange synthesis of amino-based three-dimensional covalent organic frameworks for gas chromatographic separation of isomers.

Thermally stable three-dimensional covalent organic frameworks (3D COFs) with rich pores of channels and cages are promising as stationary phases for gas chromatography (GC), which has not been explored. Here we synthesize the first amino-based 3D COF and its covalently bonded capillary via building-block exchange for GC separation of isomers.